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PromAssist, synthetic biologists assistant

In previous posts , I briefly introduced the world of synthetic biology and designing of genetic circuits. The goal of competition such as iGEM is to encourage people designing creative solutions to real-world problems using synthetic biology with the hope of moving the field out of academia into industry, much like electronics. And much like electronics, iGEM is trying to develop a library of biological parts, analogous to electronic parts such as capacitors and resistors to build any circuit. If you have ever dabbled in electronics, you'd notice that not parts are created equally; Some capacitors have higher efficiencies than others which might suit a certain application more. In this post, I want to explore one of the most important "biological parts" in my opinion:   What are promoters Promoters are regions of DNA usually found upstream of a gene that act as a switch to express whatever gene is downstream of it. Since translating DNA to mRNA requires the help of RNA ...

Modelling mycelium growth

  Why material science? Since material names are used to define periods of civilisations of the past (Stone Age, Bronze Age, etc ...), material science is considered, in my opinion, one of the species-defining endeavours. Civilizations that mastered smelting iron ended up victorious. All of a sudden, enemies had to deal with stronger swords and implantable shields. The same applies today, countries that managed to master silicon chip manufacturing ended up economically victorious. With the advent of biotechnology, largely with the help of artificial intelligence tools such as AlphaFold, there could be a promise of a new class of materials that are grown instead of manufactured. Bio-composite materials offer an alternative solution to create materials inspired by nature and can returned to it at the end of their lifespan. Such materials will tremendously accelerate reaching our sustainability goals. Mycelium Composites One such material is mycelium, which is considered nature's solu...

Butlerian Jihad: The crusade against AI and hidden tech

Image 1: Mdjourney generated picture using the prompt: "cartoon of human soldiers fighting a small robot. it shows the defeated robot in the middle and human soldiers aiming their rifles at the robot" "We must negate the machines-that-think. Humans must set their own guidelines. This is not something machines can do. Reasoning depends upon programming, not on hardware, and we are the ultimate program! Our Jihad is a "dump program." We dump the things which destroy us as humans!" ' ― Minister-companion of the Jihad. [6] That quote will be recognizable if you have read Dune by Frank Herbert . I found it suitable to bring the novel up during the extreme mixture of excitement and fear among people given the recent advance in artificial intelligence. Even an open letter was signed by many extremely influential people to halt the progress of artificial intelligence research to avoid a situation like in the cartoon above in image 1 (which is ironically AI ...